Implementation of WHO PEN is a key component of the objective 4 of the Global Action Plan. These tools will enable early detection and management of cardiovascular diseases, diabetes, chronic respiratory diseases and cancer to prevent life-threatening complications (e.g. heart attacks, stroke, kidney failure, amputations, blindness).

Effective implementation of WHO PEN, combined with other very cost effective population-wide interventions, will help even resource-constrained settings to attain the global voluntary targets related to reduction of premature mortality and prevention of heart attacks and strokes.